Applications are invited for a 3-year postdoctoral fellowship in neuroscience in the project “Modulating sleep vascular dynamics to alter brain waste clearance”. The aim of the project is to elucidate how vascular dynamics in sleep contributes to brain waste clearance in sleep through the so-called glymphatic system of the brain. This system represents a basic physiological function of sleep that may be important for the prevention of neurodegenerative disorders such as Alzheimer’s disease.

The applicant will work in a multidisciplinary team, and the main work responsibilities will be to perform in vivo two-photon microscopy experiments of sleeping mice and perform in vivo chronic neuropixels electrophysiological recordings in mice as well as performing data analyses of data generated in such experiments. Experimental work as part of the project will take place in GliaLab (https://glialab.no) at the Institute of Basic Medical Sciences, University of Oslo.

Representative articles illustrating the type of experimental work and analyses we perform can be found in some of our recent papers:

• Bojarskaite et al 2023, Nature Communications: 
  https://www.nature.com/articles/s41467-023-36643-5 
• Åbjørsbråten et al, 2022, eLife: https://elifesciences.org/articles/75055 
• Bojarskaite et al, 2020, Nature Communications: 
  https://www.nature.com/articles/s41467-020-17062-2
• Bjørnstad et al, 2021, Frontiers in Cellular Neuroscience:  https://www.frontiersin.org/articles/10.3389/fncel.2021.681066/full

Duties and responsibilities

• The candidate will perform in vivo two-photon microscopy and chronic neuropixels experiments of sleeping mice and perform data analyses of data generated in such experiments.

Oslo University Hospital is a workplace with great diversity. We believe this is crucial to solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions, and encourage all qualified candidates, regardless of background, to apply.

Kvalifikasjoner:

Qualification requirements 

• A PhD in neuroscience.
• Documented experience with in vivo chronic neuropixels electrophysiological recordings and/or in vivo two-photon microscopy experiments in unanesthetized mice. 
• Documentation of formal training and certification for working with live animals must be provided.
• Advanced understanding of neuroscience.
• Documented experience in relevant advanced data analyses in either MATLAB or Python.
• Fluent oral and written communication skills in English
  

Personlige egenskaper:

Personal skills

The following personal skills will be considered beneficial during evaluation of applications:

• Highly motivated and accurate candidate.
• Good problem-solving skills.
• Ability to work both independently and as integrated member of a multidisciplinary team.
• Good communication skills and teaching abilities.

Vi tilbyr:

What we offer

• Salary following postdoctoral candidate placement in the public service.
• Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities.

 

The application must contain:

• Cover letter statement of motivation and research interests.
• CV (summarizing education, positions and academic work)
• Copies of educational certificates (academic transcripts only)
• Complete list of publications and academic works
• List of reference persons: 2–3 references (name, relation to candidate, e-mail and phone number)